{"id":3148,"date":"2018-06-28T15:57:08","date_gmt":"2018-06-28T15:57:08","guid":{"rendered":"https:\/\/fertilab.com\/diagnostico-genetico-preimplantacional\/"},"modified":"2019-04-24T08:25:30","modified_gmt":"2019-04-24T08:25:30","slug":"diagnostic-genetic-preimplantacional-dgp","status":"publish","type":"page","link":"https:\/\/fertilab.com\/ca\/diagnostic-genetic-preimplantacional-dgp\/","title":{"rendered":"Diagn\u00f2stic gen\u00e8tic preimplantacional (DGP)"},"content":{"rendered":"
[mk_page_section vertical_align=”center” bg_image=”https:\/\/fertilab.com\/wp-content\/uploads\/2018\/06\/et-2.jpg” bg_position=”center center” bg_repeat=”no-repeat” bg_stretch=”true” bg_gradient=”vertical” video_color_mask=”#145da8″ gr_end=”rgba(20,93,168,0.25)” top_shadow=”true” min_height=”530″ full_width=”true” padding_top=”0″ padding_bottom=”0″ sidebar=”sidebar-1″][vc_column][vc_row_inner is_fullwidth_content=”false”][vc_column_inner][mk_fancy_title tag_name=”h1″ color=”#ffffff” size=”42″ force_font_size=”true” size_smallscreen=”38″ size_tablet=”36″ size_phone=”32″ font_weight=”300″ txt_transform=”none” margin_bottom=”0″ font_family=”none” align=”center” el_class=”titleWidth”]Diagn\u00f2stic gen\u00e8tic preimplantacional (DGP)[\/mk_fancy_title][mk_fancy_title tag_name=”span” color=”#ffffff” size=”18″ font_weight=”400″ txt_transform=”none” margin_bottom=”0″ font_family=”none” align=”center” el_class=”titleWidth”]Determinar l’an\u00e0lisi gen\u00e8tica de l’embri\u00f3 ens permet assegurar el seu futur[\/mk_fancy_title][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/mk_page_section][vc_row][vc_column][\/vc_column][\/vc_row][mk_page_section bg_color=”#ffffff” padding_top=”80″ padding_bottom=”80″ sidebar=”sidebar-1″][vc_column][vc_row_inner css=”.vc_custom_1529330850334{padding-bottom: 50px !important;}”][vc_column_inner width=”1\/2″][mk_image src=”https:\/\/fertilab.com\/wp-content\/uploads\/2018\/07\/ilu_embryoscope.png” image_size=”full” align=”center”][\/vc_column_inner][vc_column_inner width=”1\/2″][mk_fancy_title color=”#4a76c9″ size=”21″ font_weight=”bold” font_style=”normal” txt_transform=”uppercase” margin_top=”62″ margin_bottom=”22″ font_family=”none”]Diagn\u00f2stic Gen\u00e8tic Preimplantacional[\/mk_fancy_title][mk_fancy_title color=”#4a76c9″ size=”21″ font_weight=”300″ font_style=”italic” margin_bottom=”0″ font_family=”none”]Qu\u00e8 \u00e9s el DGP?[\/mk_fancy_title][vc_column_text css=”.vc_custom_1542186030113{margin-bottom: 0px !important;}”]Diagn\u00f2stic gen\u00e8tic preimplantacional (DGP) \u00e9s un diagn\u00f2stic que s’utilitza com a complement a la Fecundaci\u00f3 in vitro, que permet analitzar gen\u00e8ticament els embrions catalogats (sense alteracions gen\u00e8tiques) com a aptes en la fase pr\u00e8via de desenvolupament i transfer\u00e8ncia dels embrions a l’\u00fater. L’objectiu \u00e9s garantir una descend\u00e8ncia saludable i acabar amb la transmissi\u00f3 d’una determinada patologia, anomalia cromos\u00f2mica o mutaci\u00f3 gen\u00e8tica.<\/p>\n

El DGP requereix un estudi exhaustiu per part del nostre equip de metges, bi\u00f2legs i genetistes, aix\u00ed com l’establiment d’una estrat\u00e8gia de diagn\u00f2stic i terap\u00e8utica individualitzada. A continuaci\u00f3, la parella ha d’experimentar un tractament de fecundaci\u00f3 in vitro per poder cr\u00e9ixer els embrions fins a l’etapa de blastocist, que \u00e9s quan realitzarem la bi\u00f2psia embrion\u00e0ria.[\/vc_column_text][mk_fancy_title color=”#4a76c9″ size=”21″ font_weight=”300″ font_style=”italic” margin_bottom=”0″ font_family=”none”]Bi\u00f2psia embrion\u00e0ria:[\/mk_fancy_title][vc_column_text css=”.vc_custom_1542186050184{margin-bottom: 0px !important;}”]S’extreu una c\u00e8l\u00b7lula de cada embri\u00f3 per estudiar els seus cromosomes. Els embrions diagnosticats com sans (sense alteracions cromos\u00f2miques) es poden transferir a l’\u00fater per obtenir una gestaci\u00f3 evolutiva i normal.[\/vc_column_text][mk_fancy_title color=”#4a76c9″ size=”21″ font_weight=”300″ font_style=”italic” margin_bottom=”0″ font_family=”none”]DGP permet assegurar una descend\u00e8ncia saludable[\/mk_fancy_title][vc_column_text css=”.vc_custom_1542186076406{margin-bottom: 0px !important;}”]Cada dia hi ha m\u00e9s malalties heredit\u00e0ries de les quals coneixem l’alteraci\u00f3 cromos\u00f2mica que els origina. Aquestes alteracions ja es poden detectar a l’embri\u00f3. A la llista d’indicacions de malalties subsidi\u00e0ries del diagn\u00f2stic gen\u00e8tic preimplantacional es reflecteixen totes les malalties que podem diagnosticar. Si esteu interessats a obtenir informaci\u00f3 sobre una malaltia que no apareix a la llista seg\u00fcent, contacteu amb nosaltres. Els nostres genetistes estan constantment innovant i investigant.<\/p>\n

El DPG s’indica quan el diagn\u00f2stic gen\u00e8tic \u00e9s t\u00e8cnicament possible, la seva fiabilitat \u00e9s alta, les possibilitats d’\u00e8xit s\u00f3n acceptables i les t\u00e8cniques de reproducci\u00f3 assistida s\u00f3n factibles.[\/vc_column_text][mk_fancy_title color=”#4a76c9″ size=”21″ font_weight=”300″ font_style=”italic” margin_bottom=”0″ font_family=”none”]Indicacions de malalties subsidi\u00e0ries del DGP[\/mk_fancy_title][vc_column_text css=”.vc_custom_1542186149718{margin-bottom: 0px !important;}”]\u00c9s possible realitzar un DGP per qualsevol malaltia gen\u00e8tica en qu\u00e8 s’hagi caracteritzat el gen, independentment del seu patr\u00f3 d’her\u00e8ncia autos\u00f2mic dominant, autos\u00f2mic recessiu o X. Idealment, \u00e9s convenient que s’hagi identificat la mutaci\u00f3 responsable i que tamb\u00e9 s’hagin estudiat els familiars de la parella.<\/p>\n

Fins ara, s’ha aplicat DGP per a l’an\u00e0lisi de m\u00e9s de 160 malalties monog\u00e8niques diferents. El DGP nom\u00e9s s’indica quan el diagn\u00f2stic gen\u00e8tic \u00e9s t\u00e8cnicament possible, la seva fiabilitat \u00e9s alta, les possibilitats d’\u00e8xit s\u00f3n acceptables i les t\u00e8cniques de reproducci\u00f3 assistida s\u00f3n factibles.<\/p>\n

Les parelles indicades per a la realitzaci\u00f3 d’un DGP s\u00f3n aquelles amb un alt risc gen\u00e8tic de patir malalties monog\u00e8niques i anomalies cromos\u00f2miques estructurals o num\u00e8riques. Tamb\u00e9 s’indica per a parelles procedents de programes de fecundaci\u00f3 in vitro en qu\u00e8 es detecta l’exist\u00e8ncia d’avortaments de repetici\u00f3 i fallides repetides en la implantaci\u00f3. Tamb\u00e9 es pot indicar quan l’edat de la dona t\u00e9 m\u00e9s de 37 anys i quan l’estudi de la meiosi de l’home revela alteracions.<\/p>\n

Consulta la llista de malalties monog\u00e8niques detectades pel DPG.[\/vc_column_text][mk_fancy_title color=”#4a76c9″ size=”21″ font_weight=”300″ font_style=”italic” margin_bottom=”0″ font_family=”none”]Indicacions especials de DGP[\/mk_fancy_title][vc_column_text css=”.vc_custom_1542186447361{margin-bottom: 0px !important;}”]Predisposici\u00f3 a certes malalties<\/span><\/p>\n

Hi ha mutacions en certs gens que predisposen a l’aparici\u00f3 de malalties en el curs de la vida. Quan es confirma aquest comportament hereditari, la possibilitat de realitzar un DGP evitar\u00e0 l’aparici\u00f3 de la malaltia en la descend\u00e8ncia.<\/p>\n

Un exemple d’aquestes malalties que es poden evitar s\u00f3n la poliposi adenomatosa familiar, la neurofibromatosi i el c\u00e0ncer de mama d’origen gen\u00e8tic. En aquests casos, dur a terme un DGP requereix l’autoritzaci\u00f3 expressa de l’autoritat sanit\u00e0ria, amb un informe favorable de la Comissi\u00f3 Nacional de Reproducci\u00f3 Humana Assistida.<\/p>\n

Preimplantaci\u00f3 Diagn\u00f2stic gen\u00e8tic i histocompatibilitat (HLA)<\/span><\/p>\n

La legislaci\u00f3 vigent sobre t\u00e8cniques de reproducci\u00f3 assistida inclou la possibilitat de realitzar un cicle de DGP per a la determinaci\u00f3 d’ant\u00edgens d’histocompatibilitat (antigen de leuc\u00f2cits HLA-humans) amb finalitats terap\u00e8utiques per a tercers.<\/p>\n

Aquesta soluci\u00f3 s’aplica quan un familiar de primer grau, generalment un nen, pateix d’una malaltia de hematopoesis que requereix un trasplantament de medul\u00b7la \u00f2ssia o de cord\u00f3 umbilical. En aquests casos, per dur a terme el DGP es requereix l’autoritzaci\u00f3 expressa de l’autoritat sanit\u00e0ria, amb un informe previ favorable de la Comissi\u00f3 Nacional de Reproducci\u00f3 Humana Assistida.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/mk_page_section][mk_page_section vertical_align=”center” bg_image=”https:\/\/fertilab.com\/wp-content\/uploads\/2018\/06\/img_imagenembryo_backgroundblur.jpg” bg_position=”center center” bg_repeat=”no-repeat” bg_stretch=”true” top_shadow=”true” adaptive_height=”true” min_height=”600″ padding_top=”0″ padding_bottom=”0″ el_class=”barcelona video” sidebar=”sidebar-1″][vc_column][vc_row_inner][vc_column_inner][mk_fancy_title color=”#ffffff” size=”21″ font_weight=”300″ font_style=”italic” margin_top=”40″ margin_bottom=”40″ font_family=”none” align=”center”]Cada pacient pot veure l\u2019evoluci\u00f3 dels seus propis embrions en un v\u00eddeo time-lapse.[\/mk_fancy_title][vc_raw_html]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[\/vc_raw_html][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/mk_page_section][mk_page_section bg_position=”center center” bg_repeat=”no-repeat” bg_stretch=”true” min_height=”0″ full_width=”true” padding_top=”65″ padding_bottom=”65″ el_class=”contact-bottom responsive-contact” sidebar=”sidebar-1″][vc_column][mk_fancy_title color=”#7d7d7e” size=”28″ force_font_size=”true” size_smallscreen=”38″ size_tablet=”36″ size_phone=”32″ font_weight=”300″ margin_bottom=”40″ font_family=”none” align=”center”]T\u2019interessa aquest tractament?[\/mk_fancy_title][vc_column_text align=”center” el_class=”btnContact” css=”.vc_custom_1542186255068{margin-bottom: 0px !important;}”]POSA\u2019T EN CONTACTE<\/a>[\/vc_column_text][\/vc_column][\/mk_page_section][vc_row visibility=”visible-sm” el_class=”rowTelephone”][vc_column][vc_raw_html]JTNDZGl2JTIwaWQlM0QlMjJwaG9uZWJhckZpeGVkJTIyJTNFJTBBJTIwJTIwRGVtYW5hJTIwY2l0YSUyMGFsJTIwdGVsJUMzJUE4Zm9uJTIwZ3JhdHUlQzMlQUZ0JTIwJTNDYSUyMGhyZWYlM0QlMjJ0ZWwlM0E5MzI0MTE0MTQlMjIlM0U5MyUyMDI0MSUyMDE0JTIwMTQlM0MlMkZhJTNFJTBBJTNDJTJGZGl2JTNF[\/vc_raw_html][\/vc_column][\/vc_row]\n<\/div>","protected":false},"excerpt":{"rendered":"

[mk_page_section vertical_align=”center” bg_image=”https:\/\/fertilab.com\/wp-content\/uploads\/2018\/06\/et-2.jpg” bg_position=”center center” bg_repeat=”no-repeat” bg_stretch=”true” bg_gradient=”vertical” video_color_mask=”#145da8″ gr_end=”rgba(20,93,168,0.25)” top_shadow=”true” min_height=”530″ full_width=”true” padding_top=”0″ padding_bottom=”0″ sidebar=”sidebar-1″][vc_column][vc_row_inner is_fullwidth_content=”false”][vc_column_inner][mk_fancy_title tag_name=”h1″ color=”#ffffff” size=”42″ force_font_size=”true” size_smallscreen=”38″ size_tablet=”36″ size_phone=”32″ font_weight=”300″ txt_transform=”none” margin_bottom=”0″ font_family=”none” align=”center” el_class=”titleWidth”]Diagn\u00f2stic gen\u00e8tic preimplantacional (DGP)[\/mk_fancy_title][mk_fancy_title tag_name=”span” color=”#ffffff” size=”18″ font_weight=”400″ txt_transform=”none” margin_bottom=”0″ font_family=”none” align=”center” el_class=”titleWidth”]Determinar l’an\u00e0lisi gen\u00e8tica de l’embri\u00f3 ens permet assegurar el seu futur[\/mk_fancy_title][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/mk_page_section][vc_row][vc_column][\/vc_column][\/vc_row][mk_page_section bg_color=”#ffffff” padding_top=”80″ padding_bottom=”80″ […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-3148","page","type-page","status-publish","hentry"],"yoast_head":"\nDiagn\u00f2stic gen\u00e8tic preimplantacional (DGP) - 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